So I think a lot of mitochondrial energy metabolism is the bottlenecks that people can have is kind of like jammed up traffic. And a lot of times you can mega dose something. And the main problem of mega-dosing that for anyone would be it would be imbalance with something else. But if you've got a blockage in that something else, now you've just got like a train wreck happening in your mitochondria because you're activating one pathway that has to flow through the next one where you had your blockage and it's like that. So you can go online, for example, and find communities where people are raving about high-dose thiamine. And the RDA, the government recommended amount of thiamine to get is around like 1.3 milligrams. There's people out there who are like, oh, everyone should be taking 2,000 milligrams per day. But I saw one case where this happened before I knew the person, but they had fatigue so bad that they couldn't get off the couch. And so she was self-rating her energy at zero. And a practitioner said, oh, you should really try this high-dose thiamine. So she went on 1,100 milligrams a day. So not 2,000, but big, right? And a lot of people get miracles out of this. And they are vocal. They make communities on Facebook. And so people get the idea that everyone who tries it is benefiting from it. But her energy did improve a little bit, but she developed a new, completely new motor dysfunction problem, unsteady gait. It just kept getting worse the whole time she was taking the thiamine. She had an existing problem with dizziness that got a lot worse. And a major issue for her was that she had to clear out the thiamine. But the mitochondrial testing that we did on her basically showed that it explained it because it's because she had a block in the pathways that would be most sensitive to mega dosing that supplement. And so winding that back and renourishing those other pathways helped her.