| Time | Text |
|---|---|
| Basic science studies have shown that use of these products actually changes the structure and function of neurons and their connections called synapses in the brain, like permanently change their structure and function. | |
| They permanently affect the neurotransmitters being released, serotonin, noradrenaline, oxytocin. | |
| And these are not just I'm raising serotonin while I'm on the drug. | |
| These are drugs that have the potential to literally change brain function permanently. | |
| Individually, we have identified that independent of the brain actions, the drugs have peripheral actions. | |
| And in the penis of animals, and now we're finding in our study, that oxygen radical concentrations are increased in individuals who take these medicines. | |
| Oxygen radicals are very potent oxygen molecules that attach and kill smooth muscle cells in the penis, leading to increased scarring in the penis. | |
| That is not a reversible concept. | |
| So we have identified in 11, 12, 15-year-old people scarring in their penises, adversely affecting function because of use of these medicines. | |
| That's the sad part. | |
| I think you've described it as being that of a 70-year-old. | |
| We took the population of PSSD patients and identified two subgroups, similar aged people who had ED, erectile dysfunction, from trauma, motocross horse riding, bicycle riding, you know, that type of thing. | |
| And we compared to another subgroup of individuals greater than age 55 with the risk factors of hypertension, high cholesterol diabetes. |